Thrombin inhibitors

Details Thrombin inhibitors Thrombin inhibitors

1999-09-28

2000-09-12

Fan, Jane

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546256, 546194, 546261, 546193, 514318, 514335, C07D40112, A61K 314412

Patent

active

061178888

ABSTRACT:
Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure:

REFERENCES:
patent: 5260307 (1993-11-01), Ackermann et al.
patent: 5405854 (1995-04-01), Ackermann et al.
patent: 5459142 (1995-10-01), Tone et al.
patent: 5510369 (1996-04-01), Lumma et al.
patent: 5744486 (1998-04-01), Sanderson et al.
patent: 5866573 (1999-02-01), Sanderson et al.
Bernstein, Peter R. et al, "Nonpeptidic Inhibitors of Human Leukocyte Elastase . . ."J. Med. Chem., vol. 37, pp. 3313-3326 (1994).
Sanderson, P. E., et al., "Preparation Of 3-Amino-2-Pyrazinone-1-Acetamide Derivatives As Thrombin Inhibitors," Chem. Abstr., vol. 128, No. 3, pp. 532 (1998).
Sanderson, et al., Preparation of Aminopyridones as Thrombin Inhibitors, Database Caplus on STN, No. 129:136100 (1998).

Affiliated with

Also associated with

Rating

Thrombin inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thrombin inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thrombin inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-96545