Thrombin inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514255, 514637, 544383, 546312, 564245, A61K 3144, C07D21372

Patent

active

058721380

ABSTRACT:
A compound which inhibits human thrombin and which has the general structure ##STR1##

REFERENCES:
patent: 5084466 (1992-01-01), Alig
patent: 5260307 (1993-11-01), Ackermann et al.
patent: 5405854 (1995-04-01), Ackermann et al.
patent: 5459142 (1995-10-01), Tonee et al.
patent: 5510369 (1996-04-01), Lumma et al.
patent: 5518735 (1996-05-01), Sturzebecher et al.
patent: 5612363 (1997-03-01), Mohan et al.
Johnson RA et al. J. Med Chem. 29(8), pp. 1461-1468, 1986.
Cohen T and Deets GL. J. Am. Chem. Soc. 94 (3), pp. 932-937, Feb. 1972.
Efange MN et al. J. Med. Chem. 33 (12), pp. 3133-3138, 1990.
Archibald JI and Benke GA. J Med. Chem. 17 (7), pp. 736-739, 1974.
Mack et al., J. Enzyme Inhibition, "Design, Synthesis and Biological Activity of Novel Rigid Amidino-Phenylalanine . . . ", vol. 9, pp. 73-86 (1965).
Bernstein, et al., J. Med. Chem., 37, 3313-3326 "Nonpeptidic Inhibitors of Human Leukocyte Elastase . . . ", 1994.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Thrombin inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thrombin inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thrombin inhibitors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2062770

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.