Thrombin and collagen procoagulant and process for making the sa

Details Thrombin and collagen procoagulant and process for making the sa Thrombin and collagen procoagulant and process for making the sa

1998-02-27

1999-09-14

Buiz, Michael

Surgery

Instruments

Internal pressure applicator

604 96, 530383, A61M 2900

Patent

active

059515830

ABSTRACT:
A procoagulant designed to effect hemostasis at a puncture site in a patient's vasculature without the aid of manual compression is comprised of lyoplilized thrombin that is reconstituted with a buffered diluent and collagen that is mixed with the reconstituted thrombin to produce a viscous mixture. The buffered diluent is preferably of sodium phosphate and water. The procoagulant is essentially isotonic and has a pH in the range of 5-10. The method of making the procoagulant is comprised of the steps of reconstituting the lyophilized thrombin with the buffered diluent and then, mixing the reconstituted thrombin with collagen to both reduce the size of the particles of the collagen and form a fluid mixture.

REFERENCES:
patent: 5843442 (1998-12-01), Soule et al.
patent: 5861382 (1999-01-01), Cohen et al.

Affiliated with

Also associated with

Rating

Thrombin and collagen procoagulant and process for making the sa does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thrombin and collagen procoagulant and process for making the sa, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thrombin and collagen procoagulant and process for making the sa will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1505203