Threshold ligand-receptor assay

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 75, 435 79, 435 792, 435 793, 435 794, 435805, 435810, 435967, 436501, 436514, 436518, 436523, 436524, 436525, 436526, 436527, 436528, 436529, 436530, 436531, 436807, 436810, 436825, G01N 3353

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050893912

ABSTRACT:
This invention is directed to a ligand-receptor assay for determining the presence or amount of at least one target ligand, capable of competing with a ligand analogue conjugate for binding sites available on a ligand receptor, said ligand analogue conjugate comprising at least one ligand analogue coupled to a signal development element capable of emitting a detectable signal, in a fluid sample suspected of containing said target ligand, comprising the steps of:

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T. Chard, "An Introduction to Radioimmunoassay and Related Techniques" in Laboratory Techniques in Biochemistry and Molecular Biology; pp. 1-26 and 169-184, (1982).
R. Yalow et al., "General Principles of Radioimmunoassay", in Radioisotopes in Medicine: In Vitro Studies, pp. 7-41, (Jun. 1968).

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