Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Chemical analysis
Reexamination Certificate
2005-05-03
2005-05-03
Brusca, John S. (Department: 1631)
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Chemical analysis
C703S011000
Reexamination Certificate
active
06889145
ABSTRACT:
The present invention includes three-dimensional models of antibodies, such as Fc-Cε/Cε4 regions of IgE antibodies, as well as methods to produce such models. The present invention also includes muteins having increased stability and/or antibody receptor binding activity, as well as methods to produce such muteins, preferably using information derived from three-dimensional models of the present invention. Also included are nucleic acid sequences encoding muteins of the present invention and use of those sequences to produce such muteins. Also included is the use of the model to identify compounds that inhibit the binding of an antibody receptor protein to an antibody. The present invention also includes uses of such muteins and inhibitory compounds, for example, in methods to diagnose and protect animals from allergy and other abnormal immune responses.
REFERENCES:
patent: 4962035 (1990-10-01), Leder et al.
patent: 5180805 (1993-01-01), Gould et al.
patent: 5639660 (1997-06-01), Kinet et al.
patent: 5693758 (1997-12-01), Gould et al.
patent: 5978740 (1999-11-01), Armistead et al.
patent: 38 20 556 (1989-12-01), None
patent: 0 404 186 (1990-12-01), None
patent: 5113443 (1993-05-01), None
patent: 8-101194 (1996-04-01), None
patent: WO 8901520 (1989-02-01), None
patent: WO 8905352 (1989-06-01), None
patent: WO 9106570 (1991-05-01), None
patent: WO 9304173 (1993-03-01), None
patent: WO 9514779 (1995-06-01), None
patent: WO 9516203 (1995-06-01), None
patent: WO 9535367 (1995-12-01), None
patent: WO 9601643 (1996-01-01), None
patent: WO 9720859 (1997-06-01), None
patent: WO 9740033 (1997-10-01), None
patent: WO 9823964 (1998-06-01), None
patent: WO 9827208 (1998-06-01), None
patent: WO 9845707 (1998-10-01), None
patent: WO 9938974 (1999-08-01), None
patent: WO 9940117 (1999-08-01), None
patent: WO 01 68861 (2001-09-01), None
Beavil et al., 1993,Biochemical Society Transactions, vol. 21, pp. 968-972.
Blank et al., 1991,J. Biol. Chem.,vol. 266, No. 4, pp. 2639-2646
Cook et al., 1997,Biochemistry, vol. 36, pp. 15579-15588.
Dombrowicz et al., 1993,Cell, vol. 75, pp. 969-976.
Dombrowicz et al., 1997,J. Clin. Invest., vol. 99, No. 5, pp. 915-925.
Garman et al., 1998,Cell, vol. 95, pp. 951-961.
Gounni et al., 1994,Nature, vol. 367, pp. 183-186.
Greer, Jonathan, 1990,Proteins: Structure, Function, and Genetics, vol. 7, pp. 317-334.
Havel et al., 1991,J. Mol. Biol., vol. 217, pp. 1-7.
Hayashi, et al., GenBank Accession No. D16413, submitted Jun. 8, 1993.
Helm et al., 1988,Nature, vol. 331, pp. 180-183.
Heusser et al., 1997,Curr. Opin. Immunol., vol. 9, pp. 805-813.
Hill et al., 1996,Human Molecular Genetics, vol. 5, No. 7, pp. 959-962.
Hulett et al., 1994,J. Biol. Chem., vol. 269, No. 21, pp. 15287-15293.
Hulett et al., 1995,J. Biol. Chem., vol. 270, No. 36, pp. 21188-21194.
Joseph et al., 1997,Eur. J. Immunol., vol. 27, pp. 2212-2218.
Keown et al., 1997,Eur Biophys J, vol. 25, pp. 471-476.
Keown et al., 1998,Biochemistry, vol. 37, pp. 8863-8869.
Kinet, Jean-Pierre, 1999,Annu. Rev. Immunol., vol. 17, pp. 931-972.
Kochan et al.,Immunobiology of Proteins and Peptides VII, Edited by M.Z. Atassi, Plenum Press, NY, 1994, pp. 31-38.
Kochan et al., 1988,Nucleic Acids Res., vol. 16, No. 8, p. 3584.
Kuster et al., 1990,J. Biol. Chem. 265, 6448-6452.
Kuster et al., 1992,J. Biol. Chem. 267, 12782-12787.
LaCroix et al., 1993,Mol. Immunol., vol. 30, pp. 321-330.
Letourneur et al.,J. Biol. Chem., vol. 270, No. 14, pp. 8249-8256.
Mallamaci et al., 1993,J. Biol. Chem., vol. 268, No. 29, pp. 22076-22083
Mao et al., 1998,Clin. Genet., vol. 53, pp. 54-56.
Maurer et al., 1998,J. Immunol., vol. 161, pp. 2731-2739.
McDonnell et al., 1996,Nat. Struc. Biol., vol. 3, No. 5, pp. 419-426.
McDonnell et al., 1997,Biochem. Soc. Trans., vol. 25, pp. 387-392.
Murgolo et al., 1993,Proteins: Structure, Function and Genetics, vol. 17, pp. 62-74.
Nakamura et al.,Handbook of Experimental Immunology in Four Volumes, vol. 1: Immunochemistry, Ed. D.M. Weir, Chapter 27, pp. 27.1-27.20, 1987.
Oettgen et al., 1994,Nature, vol. 370, pp. 367-370.
Padlan et al., 1992 Summer,Receptor, 2(2), pp. 129-44, XP000892125.
Padlan et al., 1993 Nov.,Biochemical Society Transactions, 21(4), pp. 963-7, Ref: 19, XP000892109.
Padlan et al., 1993,Receptor, vol. 3, pp. 325-341.
Pang et al., 1993,J. Immunol. 151, 6166-6174.
Patent Abstract of Japan, vol. 095, No. 006, Jul. 31, 1995 and JP 07 072150A (Tonen Corp.; Others: 01) Mar. 7, 1995.
Patent Abstract of Japan, vol. 095, No. 007, Aug. 31, 1995 and JP 07 092167A (Kinki Univ..; Others: 01) Apr. 7, 1995.
Ravetch et al., 1998,Annu Rev Immunolo 16, 421-432.
Robertson, Michael W., 1993,J. Biol. Chem., vol. 268, No. 17, pp. 12736-12743.
Samoilovich et al.,ACI News, 4, pp. 21-25, 1992.
Sánchez-Madrid, et al., 1984,Journal of Immunological Methods, vol. 73, pp. 367-378.
Scarselli et al., 1996,FEBS, vol. 329, No. 1,2, pp. 223-226.
Schiffer et al., 1990,Proteins: Structure, Function, and Genetics, vol. 8, pp. 30-43.
Seto et al., 1995,Protein Science, vol. 4, pp. 655-670.
Schimizu et al., 1988,Proc. Natl. Acad Sci. USA 85, 1907-1911.
Shirakawa et al., 1994,Nature Genetics, vol. 7, pp. 125-130.
Stämpfli et al.,Journal of Immunology, 155, pp. 2948-2954, 1995.
Suto et al.,Jpn J Dermatol, 106, pp. 1377-1384, 1996.
Vercelli et al., 1989,Nature, vol. 338, pp. 649-651.
Garman, et al., 2000,Nature, vol. 406, pp. 259-266.
Malissard, et al., 1996,Eur. J. Biochem., vol. 239, pp. 340-348.
Jardetzky Theodore S.
Wurzburg Beth A.
Brusca John S.
Heska Corporation
Northwestern University
LandOfFree
Three-dimensional model of a Fc region of an IgE antibody... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Three-dimensional model of a Fc region of an IgE antibody..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Three-dimensional model of a Fc region of an IgE antibody... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3461928