Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system
Patent
1997-04-11
1999-05-11
Arana, Louis
Electricity: measuring and testing
Particle precession resonance
Using a nuclear resonance spectrometer system
G01V3/00
Patent
active
059031492
ABSTRACT:
Acquisition of three-dimensional image-guided localized proton spectroscopy (.sup.1 H-MRS) in the human brain is achieved on a standard clinical imager with a hybrid of chemical shift imaging (CSI) and transverse Hadamard spectroscopic imaging (HSI). 16.times.16.times.4 arrays of 3.5 and 1 ml voxels were obtained in 27 minutes. The spatially-selective HSI 90.degree. pulses were incorporated naturally into a PRESS double spin-echo sequence to subdivide the VOI into 4 partitions along its short axis. Two-dimensional CSI is performed along the other long axes. Because the hybrid excites the spins in the entire VOI, a .sqroot.N signal-to-noise-ratio (SNR) gain per given examination time is realized compared to sequentially interleaving N two-dimensional slices. A twofold gain in sensitivity is demonstrated in the brain for N=4.
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Bolinger Lizann
Goelman Gadi
Gonen Oded
Leigh John S.
Arana Louis
The Trustees of the University of Pennsylvania
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