Three-dimensional interferometric microscopy

Details Three-dimensional interferometric microscopy Three-dimensional interferometric microscopy

2011-04-12

2011-04-12

Lyons, Michael A (Department: 2877)

Optics: measuring and testing

By light interference

For dimensional measurement

C359S370000

Reexamination Certificate

active

07924432

ABSTRACT:
A statistically sparse subset of switchable optical sources in a sample is activated, and the activated switchable optical sources are excited such that optical beams are emitted from the activated switchable optical sources along at least two optical paths. A first wavefront modification in a first optical beam emitted from the activated switchable optical sources along a first optical path is introduced and a second wavefront modification in a second optical beam emitted from the activated switchable optical sources along a second optical path is introduced, the second wavefront modification being distinct from the first wavefront modification. The first and second optical beams are interfered with each other to produce a plurality of output beams, and three-dimensional position information of the optical sources is determined based on an intensity of each output beam from the plurality of output beams.

REFERENCES:
patent: 5671085 (1997-09-01), Gustafsson et al.
patent: 6570705 (2003-05-01), Bewersdorf et al.
patent: 7064824 (2006-06-01), Hell
patent: 7274506 (2007-09-01), Engelhardt
patent: 7535012 (2009-05-01), Betzig et al.
patent: 7573577 (2009-08-01), Martinez
patent: 2001/0012151 (2001-08-01), Knebel
patent: 2002/0105722 (2002-08-01), Bewersdorf et al.
patent: 2006/0038993 (2006-02-01), Hell
Sri Rama Prasanna Pavini et al., “Three-dimensional, single-molecule fluorescence imaging beyond the diffraction limit by using a double-helix point spread function,” PNAS, Mar. 3, 2009, vol. 106, No. 9, pp. 2995-2999.
Manuel F. Juette et al., “Three-dimensional sub-100 nm resolution fluorescence microscopy of thick samples,” Nature Methods, Advance Online Publication, May 11, 2008, pp. 1-3.
Manuel F. Juette et al., “Three-dimensional sub-100 nm resolution fluorescence microscopy of thick samples,” Supplementary figures and text, Nature Methods, Advance Online Publication, May 11, 2008, 11 pages.
Bo Huang et al., “Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction Microscopy,” Sciencexpress, Jan. 3, 2008, pp. 1-7.
Bo Huang et al., “Supporting Online Material for Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction Microscopy,” Sciencexpress, Jan. 3, 2008, 8 pages.

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