Combinatorial chemistry technology: method – library – apparatus – Library – per se
Reexamination Certificate
2001-10-25
2009-12-29
Lundgren, Jeffrey S. (Department: 1639)
Combinatorial chemistry technology: method, library, apparatus
Library, per se
C435S006120
Reexamination Certificate
active
07638464
ABSTRACT:
A biochip is formed with a plurality of optically clear hydrogel cells attached to the top surface of a solid substrate in the form of an array. Each of the cells is formed of a hydrogel of polyethylene glycol, polypropylene glycol or a copolymer thereof having reactive isocyanate groups. Binding entities are immobilized in these cells, which entities are effective to selectively hybridize to or sequester a target biomolecule. Different binding entities are immobilized in different cells in an array to create a biochip that can be used to assay for a number of target biomolecules.
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Dong Xiaofan
Fagnani Roberto
Hahn Soonkap
Matsumoto Sandra
Pircher Tony
Biocept, Inc.
Fitch Even Tabin & Flannery
Lundgren Jeffrey S.
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