Plastic and nonmetallic article shaping or treating: processes – Forming continuous or indefinite length work – Layered – stratified traversely of length – or multiphase...
Reexamination Certificate
2011-06-28
2011-06-28
Woodward, Cherie M (Department: 1647)
Plastic and nonmetallic article shaping or treating: processes
Forming continuous or indefinite length work
Layered, stratified traversely of length, or multiphase...
C264S041000, C264S113000, C264S211000, C264S234000, C264S255000, C264S308000, C264S497000, C623S016110
Reexamination Certificate
active
07968026
ABSTRACT:
The invention relates to the use of Fused Deposition Modeling to construct three-dimensional (3D) bioresorbable scaffolds from bioresorbable polymers such as polycaprolactone (PCL), or from composites of bioresorbable polymers and ceramics, such as polycaprolactone/hydroxyapatite (PCL/HA). Incorporation of a bioresorbable ceramic to produce a hybrid/composite material support provides the desired degradation and resorption kinetics. Such a composite material improves the biocompatibility and hard tissue integration and allows for increased initial flash spread of serum proteins. The basic resorption products of the composite also avoids the formation of an unfavorable environment for hard tissue cells due to a decreased pH. The scaffolds have applications in tissue engineering, e.g., in tissue engineering bone and cartilage.
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Hutmacher Dietmar Werner
Tam Kock Fye
Tan Kim Cheng
Teoh Swee Hin
Zein Iwan
Hamilton Brook Smith & Reynolds P.C.
Osteopore International Ltd.
Woodward Cherie M
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