Chemistry: molecular biology and microbiology – Apparatus – Differentiated tissue perfusion or preservation apparatus
Reexamination Certificate
2008-05-06
2008-05-06
Monshipouri, Maryam (Department: 1656)
Chemistry: molecular biology and microbiology
Apparatus
Differentiated tissue perfusion or preservation apparatus
C600S029000, C435S298200
Reexamination Certificate
active
07368279
ABSTRACT:
This invention relates to a three dimensional bioengineered sphincter such as a bioengineered internal anal sphincter (IAS) and three-dimensional physiological models of smooth muscle cells. The invention also related to methods for generating a bioengineered sphincter and smooth muscle rings in culture. In addition, the invention provides for methods of using a bioengineered sphincter or bioengineered smooth muscle ring to identify agents that modify contractile force and relaxation in smooth muscle cells.
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Baar Keith
Bitar Khalil N.
Hecker Louise
Somara Sita
Marshall & Gerstein & Borun LLP
Monshipouri Maryam
The Regents of the University of Michigan
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