Three carbon precursor synthons

Details Three carbon precursor synthons Three carbon precursor synthons

2008-04-04

2010-12-14

Puttlitz, Karl J (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C562S598000

Reexamination Certificate

active

07851647

ABSTRACT:
Alkoxy[13C]methyl phenyl sulfone is a precursor to the production of Lithium (E)-β-Alkoxy[1,2,3-13C3]acrylate and thence Alkoxy (E)-β-Alkoxy[1,2,3-13C3]acrylate. Alkoxy (E)-β-Alkoxy[1,2,3-13C3]acrylate can then serve as a precursor for the production of a number of other isotopically labeled compounds. Similar chemistry using Alkoxy[14C]methyl phenyl sulfone as the precursor can yield14C labeled compounds. High purity precursors ensure that the new compounds are also highly pure.

REFERENCES:
patent: 4113863 (1978-09-01), Baumgarth et al.
patent: 6312867 (2001-11-01), Kinsho et al.
patent: 2007/0004929 (2007-01-01), Martinez et al.
PCT—Notification of Transmittal of the International Search Report and the Written Opinion of the International Searching Authority, or the Declaration, Date of Mailing: Jul. 7, 2008.

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