Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-06-10
1992-02-25
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549 27, 514908, A61K 3138, C07D33516
Patent
active
050914103
ABSTRACT:
1-[[(Dialkylamino)alkyl]amino]-4-substituted-thioxanthen-9-ones are disclosed as antitumor agents. Compositions containing the thioxanthenones and methods of treating tumors and cancer in mammals with the thioxanthenones are also disclosed.
REFERENCES:
patent: 3577441 (1971-05-01), Kaminsky et al.
patent: 3577558 (1971-05-01), Rosi
patent: 4582851 (1986-04-01), Worth
Blanz & French, "A Systematic Investigation of Thioxanthen-9-ones and Analogs as Potential Antitumor Agents", J. Med. Chem., 6, 185-191 (1963).
Miller Theodore C.
Ross Michael E.
DuPont Paul E.
Hansen Philip E.
Hollrah Glennon H.
Russell Mark W.
Sterling Winthrop Inc.
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