Thiourea compounds and the pharmaceutical compositions...

Details Thiourea compounds and the pharmaceutical compositions... Thiourea compounds and the pharmaceutical compositions...

2006-06-27

2006-06-27

Tsang, Cecilia (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

N-c doai

C564S027000, C564S372000, C564S032000, C564S039000, C564S047000

Reexamination Certificate

active

07067553

ABSTRACT:
The present invention relates to thiourea compounds and the pharmaceutical compositions containing the same, and particularly, to novel thiourea compounds as an antagonist against vanilloid receptor (VR) and the pharmaceutical compositions thereof. As diseases associated with the activity of vanilloid receptor, pain, acute pain, chronic pain, neuropathic pain, post-operative pain, migraine, arthralgia, neuropathies, nerve injury, diabetic neuropathy, neurodegeneration, neurotic skin disorder, stroke, urinary bladder hypersensitiveness, irritable bowel syndrome, a respiratory disorder such as asthma or chronic obstructive pulmonary disease, irritation of skin, eye or mucous membrane, fervescence, stomach-duodenal ulcer, inflammatory bowel disease and inflammatory diseases can be enumerated. The present invention provides a pharmaceutical composition for prevention or treatment of these diseases.

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Accession No. (AN) 2004:429173 CHEMCATS, Jan. 1, 2004.
Accession No. (AN) 2003:2480724 CHEMCATS, Nov. 12, 2004.

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