Thiopyrano[2,3,4-c,d]indoles as inhibitors of leukotriene biosyn

Details Thiopyrano[2,3,4-c,d]indoles as inhibitors of leukotriene biosyn Thiopyrano[2,3,4-c,d]indoles as inhibitors of leukotriene biosyn

1991-06-13

1993-04-13

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

C-o-group doai

5142378, 514253, 514321, 514338, 514411, 514826, 514886, 544 60, 544111, 544372, 546189, 546194, 546198, 548431, 548436, C07D40100, A61K 3154

Patent

active

052023214

ABSTRACT:
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, psoriasis, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.

REFERENCES:
patent: 5021420 (1991-06-01), Comte et al.

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