Thiophene sulfonamide antiglaucoma agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514444, 549 59, 549 60, 549 65, A61K 3138, C07D40900, C07D33332

Patent

active

048472891

ABSTRACT:
Aryl (or aralkyl)-sulfonylthiophene-2-sulfonamides containing a basic functional group as a substituent are efficacious in the treatment of elevated intraocular pressure and glaucoma following topical ocular administration.

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J. Med. Chem., 1981, 24, 959-964, Barnish et al.

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