Thiophene substituted cycloamines, compositions and use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514307, 514314, 514326, 514422, 544146, 546148, 546165, 546212, 548468, A01N 4340, A01N 4384, C07D40906, C07D41306

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active

053843150

ABSTRACT:
A class of compounds having the structural formula ##STR1## in which R is C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.6 cycloalkyl, phenyl or substituted phenyl; N, R.sup.1 and R.sup.2 form a monocyclic or bicyclic nitrogen heterocycle which is at least partially saturated and which may contain oxygen or sulfur or be substituted with lower alkyl; and physiologically acceptable salts thereof is disclosed.
A process for forming the thiophene substituted cycloamines of the subject invention is described. A composition comprising the compound of the subject invention and a suitable carrier therefor is taught.
A method of controlling phytopathogenetic fungi is disclosed. In this method a fungicidally effective amount of the compound of the present invention is applied to the locus to be protected.

REFERENCES:
patent: 2526319 (1950-10-01), Beatty III
patent: 4202894 (1980-05-01), Pfiffner
patent: 4950671 (1990-08-01), Lai et al.
J. Org. Chem., pp. 3820-3821, vol. 36, No. 24, entitled Side-Chain Amination during the Reaction of Methylbromothiophenes with Potassium Amide, by M. G. Reinecke, H. W. Adickes and C. Pyun, published 1971.
Agricultural Chemicals, Book IV--Fungicides, Thomson Publications, 1991 Revision, by W. T. Thomson, pp. 142-143.

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