Thiophene ethanolamines

Details Thiophene ethanolamines Thiophene ethanolamines

1977-02-15

1978-06-06

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603322A, 2603322C, 424250, 424274, 424275, C07D33320, C07D33328, C07D40512, C07D40912

Patent

active

040936287

ABSTRACT:
Thiophene ethanolamines substituted on the nitrogen atom with an alkyl or aralkyl radical and optionally substituted on the thiophene portion, are disclosed. The thiophene ethanolamines possess antihypertensive and .beta.-receptor blocking activities. Methods for their preparation and use are given.

REFERENCES:
patent: 3644353 (1972-02-01), Lunts et al.
patent: 3644520 (1972-02-01), Hartley et al.
patent: 3687945 (1972-08-01), Thiele et al.
patent: 3766173 (1973-10-01), Thiele et al.
Arya et al., J. Pharm. Sci., vol. 58, pp. 432-440, (1969).
Das et al., J. Med. Chem., vol. 14, pp. 890-891, (1971).
Thiele et al., Chem. Abstracts, vol. 71, Abstract No. 91188 X, (1969).
Bagli et al., J. Med. Chem., vol. 19, pp. 876-882, (1976).

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