Thiophene derivatives as S1P1/EDG1 receptor agonists

Details Thiophene derivatives as S1P1/EDG1 receptor agonists Thiophene derivatives as S1P1/EDG1 receptor agonists

2011-08-23

2011-08-23

Chu, Yong (Department: 1622)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S143000, C549S060000

Reexamination Certificate

active

08003800

ABSTRACT:
The invention relates to thiophene derivatives of formula (I)/their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents wherein: A represents *—CO—CH═CH—, *—CO—CH2CH2—, *—CO—CH2—NH—, wherein the asterisks indicate the bond that is linked to the thiophene group of Formula (I), and R1-R3 are as defined in the claims.

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