Thiophene derivatives

Details Thiophene derivatives Thiophene derivatives

1974-07-23

1976-06-15

Thomas, Jr., James O.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424275, 260329AM, 260332S, C07D33324

Patent

active

039637506

ABSTRACT:
Compounds of the formula: ##SPC1##
Wherein R.sub.1 is NHR.sub.5 or OR.sub.5 where R.sub.5 is a hydrogen atom or alkyl group of 1-6 carbon atoms; R.sub.2 is a hydrogen atom or a CO.R.sub.6 group where R.sub.6 is an alkyl group of 1-6 carbon atoms; R.sub.3 is a phenyl group substituted by 1 or 2 halogen atoms or methyl, trifluoromethyl or methoxyl groups; and R.sub.4 is a hydrogen atom or an alkyl group of 1-6 carbon atoms or a phenyl group optionally substituted by 1 or 2 halogen atoms or methyl, trifluoromethyl or methoxyl groups; and salts thereof; have been found to possess valuable anti-inflammatory properties. The preparation and use of such compounds is described.

REFERENCES:
patent: 3832354 (1974-08-01), Gadient et al.
Gewald et al., "Chemical Abstracts," vol. 64, (1966), p. 8118.

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