Thiophene compounds and thrombopoietin receptor activators

Details Thiophene compounds and thrombopoietin receptor activators Thiophene compounds and thrombopoietin receptor activators

2011-06-28

2011-06-28

Powers, Fiona T (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S255010, C514S378000, C514S397000, C514S422000, C514S444000, C544S146000, C544S379000, C546S280400, C548S240000, C548S365700, C548S530000, C549S059000, C549S060000

Reexamination Certificate

active

07968542

ABSTRACT:
A compound represented by the formula (I) (wherein R1, R2, R3and R4are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.

REFERENCES:
patent: 7351841 (2008-04-01), Owada et al.
patent: 2003/0195231 (2003-10-01), Takemoto et al.
patent: 2004/0063764 (2004-04-01), Takemoto et al.
patent: 2004/0077697 (2004-04-01), Koshio et al.
patent: 2004/0082626 (2004-04-01), Takemoto et al.
patent: 2005/0153977 (2005-07-01), Sugasawa et al.
patent: 1 207 155 (2002-05-01), None
patent: 10-72492 (1998-03-01), None
patent: 11-1477 (1999-01-01), None
patent: 11-152276 (1999-06-01), None
patent: 2001-97948 (2001-04-01), None
patent: 2003/238565 (2003-08-01), None
patent: WO 96/40189 (1996-12-01), None
patent: WO 96/40750 (1996-12-01), None
patent: WO 98/25965 (1998-06-01), None
patent: WO 99/11262 (1999-03-01), None
patent: WO 00/35446 (2000-06-01), None
patent: WO 00/66112 (2000-11-01), None
patent: WO 01/07423 (2001-02-01), None
patent: WO 01/17349 (2001-03-01), None
patent: WO 01/21180 (2001-03-01), None
patent: WO 01/34585 (2001-05-01), None
patent: WO 01/39773 (2001-06-01), None
patent: WO 01/53267 (2001-07-01), None
patent: WO 01/89457 (2001-11-01), None
patent: WO 02/49413 (2002-06-01), None
patent: WO 02/059099 (2002-08-01), None
patent: WO 02/059100 (2002-08-01), None
patent: WO 02/062775 (2002-08-01), None
patent: WO 02/085343 (2002-10-01), None
patent: WO 03/062233 (2003-07-01), None
patent: 2004 033433 (2004-04-01), None
patent: WO 2004/033433 (2004-04-01), None
patent: 2004 108683 (2004-12-01), None
patent: WO 2004/108683 (2004-12-01), None
patent: 2006 064957 (2006-06-01), None
patent: WO 2006/064957 (2006-06-01), None
Kaushansky, Kenneth, “Thrombopoietin”, New England Journal of Medicine, 746-754, Sep. 10, 1998.
van den Oudenrijn, Thrombopoietin Receptor, retrieved Jan. 18, 2007 fro internet, ,http://mpr.nci.nih.gov/prow/guide/11586825—g.htm., Protein Reviews On the Wev, p. 1-6.
Souillac, et al., Characterization of Delivery Systems, Differential Scanning Calorimetry, pp. 217-218 (in Encyclopedia of Controlled Drug Delivery, 1999, John Wiley & Sons, pp. 212-227).
Vippagunta et al., Advanced Drug Delivery Reviews, 48 (2001), pp. 3-26.
Jose E. Cardier, “Effects of Megakaryocyte Growth and Development Factor (Thrombopoietin) on Liver Endothelial Cells in Vitro”, Microvascular Research, vol. 58, 1999, pp. 108-113.
Maria Felice Brizzi, et al., “Thrombopoietin Stimulates Endothelial Cell Motility and Neoangiogenesis by a Platelet-Activating Factor-Dependent Mechanism”, Circulation Research, vol. 84, 1999, pp. 785-796.
“Blood”, Journal of the American Society of Hematology, vol. 98, No. 11, Nov. 16, 2001, pp. 71a-72a and a cover page.
U.S. Appl. No. 12/303,436, filed Dec. 4, 2008, Miyaji, et al.
U.S. Appl. No. 12/492,435, filed Jun. 26, 2009, Owada, et al.

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