Thiophene-based tricyclic compounds and pharmaceutical...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S346000, C544S295000, C544S060000, C544S115000, C514S233200, C514S250000

Reexamination Certificate

active

06933294

ABSTRACT:
Compounds having the formula (I),and pharmaceutically-acceptable salts, hydrates and prodrugs thereof, are useful as anti-inflammatory agents, in which R1, R2, and R3are hydrogen, halogen, alkyl, or perfluoroalkyl; R4is an optionally substituted alkyl or cycloalkyl group; X is a linker; A is an aryl, heteroaryl, heterocycle, cycloalkyl, or is absent; and R7is a substituent on A as defined in the specification.

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