Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-09-11
1994-07-26
Ford, John M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540598, 544 584, 544 60, 544357, 544121, 544364, 544372, A61K 31495, C07D40114
Patent
active
053327322
ABSTRACT:
Compounds of the general formula I ##STR1## wherein A is N; Ar is aryl, substituted aryl or benzofuranyl, wherein the substituents are selected from C.sub.1 -C.sub.8 alkoxy; B is CO or CH.sub.2 and HET is selected from any of piperizine, piperidine, hexahydroazepine, morpholine, thiomorpholine or pyrrolidine, which may be substituted with one of more oxo groups are disclosed as novel antipsychotic agents. Pharmaceutical compositions and methods of treating convulsions employing such compounds of formula I are also disclosed.
REFERENCES:
patent: 4895846 (1990-01-01), Poindexter et al.
patent: 5144035 (1992-09-01), Mase et al.
Rasmussen C. Royce
Reitz Allen B.
Scott Malcolm K.
Villani, Jr. Frank J.
Ford John M.
McNeilab Inc.
Palo Ralph R.
Sripada P. K.
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