Thiopeptide compounds

Details Thiopeptide compounds Thiopeptide compounds

2006-04-18

2006-04-18

Marx, Irene (Department: 1651)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S002600, C514S183000, C435S071300, C435S252500

Reexamination Certificate

active

07030085

ABSTRACT:
A microorganism belonging to the genusBacillusis cultured and thiopeptide compounds QN3323 and thiocillin I/II compounds are collected from the culture medium. The compounds are useful as drugs to treat infections caused by multidrug-resistant bacteria.

REFERENCES:
patent: WO 97/48408 (1997-12-01), None
Shoji J. et al., Isolation of Three New Antibiotics, Thiocillins I, II, and III, Related to Micrococcin P (Studies on Antibiotics from the GenusBacillus. VIII), J, Antibiotics, Apr. 1976, vol. 29, No. 4, pp. 366 to374.
Shoji J. et al., “Structural Studies on Thiocillins I, II and III (Studies on Antibiotics from the GenusBacillus. XXIX)”, J, Antibiotics, Sep. 1981, vol. 34 No. 9, pp. 1126 to 1136.
Bycroft B.W. et al., “The Structures of the Highly Modified Peptide Antibiotics Micrococcin P1and P2”, J.C.S. Chem. Comm., 1978, No. 6, pp. 256 to 258.
Ciufolini M.A. et al., “Synthesis of the Bycroft-Gowland Strucutre of Micrococcin P1”, Organic Letters, 1999, vol. 1, No. 11, pp. 1843 to 1846.

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