Thiolic derivatives or erythromycin having therapeutic activity

Details Thiolic derivatives or erythromycin having therapeutic activity Thiolic derivatives or erythromycin having therapeutic activity

1982-02-02

1983-07-12

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 72, 536 73, 536 74, A61K 3171, C07H 1708

Patent

active

043930530

ABSTRACT:
The thiolic salts of erythromycin and of the propionic ester of erythromycin with thenoyl alpha-mercaptopropionylglycine find therapeutical use in the cases in which erythromycin or its propionic ester are used and are generally endowed with very low toxicity and high hematic levels.

REFERENCES:
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patent: 2743268 (1956-04-01), Stieff
patent: 2830982 (1958-04-01), Stainbrook et al.
patent: 3558594 (1971-01-01), Jones et al.
patent: 3847896 (1974-11-01), Sinkula
patent: 4261982 (1981-04-01), Luedders et al.
patent: 4264765 (1981-04-01), Bodor et al.
Kikuchi et al., "Chem. Abst.", vol. 93, 1980, P38279f.
Labadarios et al., "Chem. Abst.", vol. 85, 1976, P153992(e).
Zanolo et al., "Chem. Abst.", vol. 95, 1981, P54571s.

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