Thiolic derivatives of erythromycin having therapeutic activity,

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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536 72, 536 73, 536 74, A61K 3171, C07H 1708

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active

044761201

ABSTRACT:
The thiolic salts of erythromycin and of the propionic ester of erythromycin with thenoyl alpha-mercaptopropionylglycine find therapeutical use in the cases in which erythromycin or its propionic ester are used and are generally endowed with very low toxicity and high hematic levels.

REFERENCES:
patent: 2653899 (1953-09-01), Bunch et al.
patent: 2743268 (1956-04-01), Stieff
patent: 2830982 (1958-04-01), Stainbrook et al.
patent: 3558594 (1971-01-01), Jones et al.
patent: 4261982 (1981-04-01), Luedders et al.
patent: 4264765 (1981-04-01), Bodor et al.
Kikuchi et al., "Chem. Abst.", vol. 93, 1980, p. 38279f.

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