Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-07-22
2000-01-11
Geist, Gary
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142392, 514345, 514369, 514386, 514486, 514543, 514546, 514568, 514570, 514571, 514618, 514630, 514707, 514709, 544158, 544159, 544160, 546290, 546339, 548186, 5483164, 560 11, 560 12, 560254, 562429, 568 23, 568 29, 568 31, 568 32, A61K 31535, A01N 4340, A01N 4378, A01N 4350, A01N 3710, A01N 3702, A01N 3718, A01N 4112
Patent
active
060136499
ABSTRACT:
This invention is directed to proteinase (protease) inhibitors, and more particularly to thiol sulfone inhibitors for matrix metalloproteinase 13(MMP-13), compositions of proteinase inhibitors, intermediates for the syntheses of proteinase inhibitors, processes for the preparation of proteinase inhibitors and processes for treating pathological conditions associated with pathological matrix metalloproteinase activity related to MMP-13.
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Abbas S. Zaheer
DeCrescenzo Gary A.
Freskos John N.
Getman Daniel P.
Heintz Robert M.
Davis Brian J.
Geist Gary
Monsanto Company
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