Thioheterocyclic near-infrared dyes

Details Thioheterocyclic near-infrared dyes Thioheterocyclic near-infrared dyes

1996-10-18

1998-07-07

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548186, 548193, 548201, 5462697, C07D27704, C07D40100

Patent

active

057771278

ABSTRACT:
Disclosed is a novel near-infrared absorbing dye of formula: ##STR1## wherein X.sup.1, x.sup.2 independently represents --CR.sup.8 R.sup.9 --, --S--, --Se--, --NR.sup.10 --, --CH.dbd.CH-- or --O--;

REFERENCES:
patent: 4882265 (1989-11-01), Laganis et al.
L. Strekowski et al., Facile Derivatizations of Heptamethine Cyanine Dyes, Synthetic Communictions, 22917), pp. 2593-2598, 1992.
L. Strekowski et al., Substitution Reactions of a Nucleofugal Group in Heptamethine Cynanine Dyes. Synthesis of an Isothiocyanato Derivative for Labeling of Proteins with a Near-Infrared Chromophore, J. Org. Chem., 57, pp. 4578-4580, 1992.
R. J. Williams, et al., Comparison of Covalent and Noncovalent Labeling with Near-Infrared Dyes for the High-Performance Liquid Chromatographic Determination of Human Serum Albumin, Anal. Chem., vol. 65, pp. 601-605, 1993.
Slominskii et al., "Polymethine Dyes With Hydrocarbon Bridges . . . ", CA, vol. 91 (1979), p. 91, ABS#22390h.

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