Thioether derivatives of tylosin

Details Thioether derivatives of tylosin Thioether derivatives of tylosin

1985-02-19

1986-06-10

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 71, A61K 3170, C07H 1708

Patent

active

045943389

ABSTRACT:
11-Thioether and certain C-20 acetal and thioacetal derivatives of tylosin and demycarosyltylosin are effective antibacterial agents. Processes for preparing, formulations containing, and methods of treating bacterial infections with these derivatives are provided.

REFERENCES:
patent: 4196280 (1980-04-01), Umezawa et al.
patent: 4366309 (1982-12-01), Ganguly et al.
patent: 4443436 (1984-04-01), Kirst et al.
patent: 4454314 (1984-06-01), Nagel
patent: 4515941 (1985-05-01), Fujiwara et al.
Rossoff, "Handbook of Veterinary Drugs", Springer Publishing Co., N.Y., N.Y., 1974, pp. 628-629.
Tanaka, et al., "Synthesis of 9-Substituted Josamicin, 13-Substituted Isojosamycin and Their Tetrahydro Derivatives," J. Antibiotics 34(9), 1137-1151 (1981).
Omoto et al., "Modification of the Macrolide Antibiotic Midecamycin III, Formation of Neoisomidecamycin," J. Antibiotics 35(11), 1521-1526 (1982).
Fukagawa et al., "Deepoxidation of 16-Membered Epoxyenone Macrolide Antibiotics," J. Antibiotics 37(2), 108-135 (1984).
Derwent Abstract 85-071701/12 (Toyo Jozo) Abstracting Japanese Patent J6 0026-000-A published Feb. 8, 1985.

Affiliated with

Also associated with

Rating

Thioether derivatives of tylosin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thioether derivatives of tylosin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thioether derivatives of tylosin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2406287