Thiochroman compounds

Details Thiochroman compounds Thiochroman compounds

1971-03-31

1976-06-01

Moatz, Harry I.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424275, C07D33506

Patent

active

039608913

ABSTRACT:
(3-amino-2-hydroxy propyloxy) thiochromans of the formula ##SPC1##
Wherein A is hydrogen or halogen, R.sub.1 is hydrogen or lower alkyl, and R.sub.2 is lower alkyl or cyclo lower alkyl.
These compounds possess cardiovascular properties and may be used as blockers of cardiac .beta. adrenergic receptors.

REFERENCES:
patent: 1129072 (1968-10-01), Turner
patent: 3328417 (1967-06-01), McLoughlin et al.
patent: 3340266 (1967-09-01), Howe et al.
patent: 3398161 (1968-08-01), Turner
patent: 3705167 (1972-12-01), Malen et al.
Crowther et al., J. Med. Chem., vol. 15, pp. 260-266 (1972).
Howe et al. II, J. Med. Chem., vol. 13, pp. 169-176 Mar. 1970).

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