Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – N-c doai
Patent
1991-04-22
1992-10-06
Brust, Joseph P.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
N-c doai
514811, 424 10, A61K 3127
Patent
active
051532190
ABSTRACT:
A method is provided for deterring ethanol ingestion by a human, comprising administering to said human an amount of a compound of the formula (R.sup.1) R.sup.2)NC(X)S(O)R.sup.3 effective to cause the disulfiram-ethanol reaction in said human, wherein R.sup.1, R.sup.2 and R.sup.3 are each (C.sub.1 -C.sub.4) alkyl groups, e.g., methyl, ethyl, propyl, isopropyl, butyl, i-butyl and t-butyl.
REFERENCES:
patent: 4565689 (1986-01-01), Revici
C.A. 77, Nilsson, et al., 151635b, (1972).
C.A. 82, Gozzo, et al., 169773h, (1975).
C.A. 103, Showa, et al., 22177k, (1985).
F. Gozzo et al., Chemistry and Industry, (1975), pp. 221-226.
T. M. Kitson et al., Biochem. J., 278, (1991), pp. 189-192.
M. D. Faiman et al., Toxicologist Abstract; 10, 174 (1990); No. 693.
B. W. Hart et al., FASEB Journal Abstract, 4, A744 (1990).
B. W. Hart et al., Alcohol, pp. 165-169, (1990).
B. W. Hart et al., Alcoholism: Clin. and Exp. Res., 12, 317 (1988).
J. J. Yourick et al., Alcohol, 4, pp. 463-467.
J. J. Yourick et al., Biochem. Pharmacol., 38, pp. 413-421, (1989).
B. Johansson et al., Biochem. Pharmacol.. 38, pp. 1053-1059, (1989).
B. Johansson, Pharmacol. and Toxicol., 64, pp. 471-474 (1989).
A. Helander et al., Biochem. Pharmacol., 38, pp. 2195-2198, (1989).
E. N. Peterson, Europ. J. Pharmacol., 166, pp. 419-425, (1989).
J. E. Casida et al., Pesticide Biochem. and Physiol., 5, pp. 1-11, (1975).
J. E. Casida et al., Science, 184, pp. 572-574, (1974).
J. E. Peachey et al., J. Clin. Psychopharmacol., 1, pp. 368-375, (1981).
M. Faiman et al., Alcoholism: Clin. and Exp. Res., 7, pp. 307-311, (1983).
J. F. Brien et al., Europ. J. Clin. Pharmacol., 14, pp. 133-141 (1978).
P. Klason, J. Prak. Chemie, 36, pp. 57-64, (1987).
S. O. Tottmar et al., Biochem. J., 135, pp. 577-586, (1983).
C. O. P. Eriksson et al., Anal. Biochem., 80, pp. 116-124, (1977).
Faiman Morris D.
Hart Bruce W.
Madan Ajay
Brust Joseph P.
Faiman Morris D.
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