Thioarabinofuranosyl compounds and use thereof

Details Thioarabinofuranosyl compounds and use thereof Thioarabinofuranosyl compounds and use thereof

2006-11-21

2006-11-21

Pryor, Alton (Department: 1616)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S043000

Reexamination Certificate

active

07138385

ABSTRACT:
Patients suffering from cancer are treated by being administered a compound represented by the following formula:wherein each R individually is H or an aliphatic or aromatic acyl group;A is selected from the group consisting ofwherein X is selected from the group consisting of hydrogen, fluorine, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, cyano and nitro. The above compounds also inhibit DNA replication in mammalian cells.

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