Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
2005-02-16
2009-12-15
Solola, Taofiq A (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
C564S074000
Reexamination Certificate
active
07632865
ABSTRACT:
To provide cytokine production inhibitors useful as preventive or therapeutic medicines for diseases accompanied by hyperactivated immune functions.A cytokine production inhibitor containing, as an active ingredient, a thioamide compound represented by the formula (I) or a salt thereof:wherein A is N, NO, C—NO2or C—CN; Hal is a halogen; M1is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, aryl, heterocyclyl, amino, O, S, SO or SO2; M2is amino, O, S or a single bond; R1is a halogen, alkyl or the like; each of R2, R3, R4and R5is independently H, alkyl or the like; R6is a halogen, alkyl or the like; Cy is cycloalkyl, cycloalkenyl, aryl or heterocyclyl; each of k, p and q is independently an integer of from 0 to 3; and r is an integer of from 0 to 5.
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Azuma Kumiko
Kato Fuminori
Kimura Hirohiko
Mori Shinya
Okada Takashi
Ishihara Sangyo Kaisha Ltd.
Oblon, Spivak McClelland, Maier & Neustadt, L.L.P.
Solola Taofiq A
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