Thioalkylamide of nicotinic acid 1-oxide, its salts, and pharmac

Details Thioalkylamide of nicotinic acid 1-oxide, its salts, and pharmac Thioalkylamide of nicotinic acid 1-oxide, its salts, and pharmac

1982-03-03

1984-10-02

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546283, A61K 31455, C07D40512

Patent

active

044747900

ABSTRACT:
The invention relates to thioalkylamide of nicotinic acid 1-oxide with H.sub.2 receptor blocking activity, of formula: ##STR1## and to its pharmaceutically acceptable salts, to a process for preparing same by reaction of 2-(5-dimethylaminomethylfuran-2-ylmethylthio)ethylamine with a functional derivative of nicotinic acid 1-oxide and possible salification, and to pharmaceutical compositions containing same.

REFERENCES:
patent: 4318858 (1982-03-01), Hirai et al.
Bickel, Pharmacological Reviews, vol. 21, No. 4, pp. 325-355, Williams & Wilkins Co., Publishers, (Dec. 1969).
Burgers Medicinal Chemistry, Fourth Edition, Part III, pp. 537-540, Wiley-Interscience, Publishers, RS 403 B8, (1979).

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