[(Thioalkyl)thioacetyl)]cephalosporin derivatives

Details [(Thioalkyl)thioacetyl)]cephalosporin derivatives [(Thioalkyl)thioacetyl)]cephalosporin derivatives

1974-08-08

1979-10-16

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544 28, 424246, C07D50128, C07D50132, C07D50134, A61K 31545

Patent

active

041714350

ABSTRACT:
[(Thioalkyl)thioacetyl]cephalosporin derivatives of the formula ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, tri(lower alkyl)silyl, a salt forming ion, or the group ##STR2## R.sub.1 is hydrogen, lower alkyl, phenyl, thienyl or furyl; R.sub.2 and R.sub.6 each is hydrogen or lower alkyl; R.sub.3 and R.sub.5 each is lower alkyl, phenyl or phenyl-lower alkyl and R.sub.4 is hydrogen, hydroxy or lower alkanoyloxy; are useful as antimicrobial agents.

REFERENCES:
Lewis et al., Antimicrobial Agents and Chemeotherapy, (1968), pp. 109-114, (1969).

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