Thioalkyl alpha substituted pyrimidine compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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5142325, 5142322, 5142338, 5142342, 5142345, 5142358, 51425214, 5142278, 5142282, 5142285, 51425216, 51425217, 514256, 514257, 514258, 514259, 514261, 514266, 544315, 544264, 544278, 544316, 544296, 544255, 544317, 544256, 544262, 544318, 544295, 544121, 544253, 544122, 544115, 544116, 544123, 544 80, 544117, 544 586, 544 81, 544118, 544 90, 544 61, C07D23934, C07D40312, A61K 31505

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06124306&

ABSTRACT:
The subject invention relates to pyrimidine-thioalkyl and alkylether compounds of Formula I ##STR1## and pyrimidine-thioalkyl and alkylethers of Formula I, where R.sub.4 is selected from the group consisting of --H or --NR.sub.15 R.sub.16 where R.sub.15 is --H and R.sub.16 is --H, C.sub.1 -C.sub.6 alkyl, --NH.sub.2 or R.sub.15 and R.sub.16 taken together with the --N form 1-pyrrolidino, 1-morpholino or 1-piperidino; and

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