Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-07-19
2011-07-19
Shiao, Rei-tsang (Department: 1628)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S252130, C514S414000, C514S438000
Reexamination Certificate
active
07981907
ABSTRACT:
The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions that include substituted biaryl-methanesulfinyl acetamides of Formula (I):wherein Ar, Y, R1, R2, R4, R5, q and x are as defined herein; and their use in the treatment of diseases, including treatment of sleepiness associated with narcolepsy, obstructive sleep apnea, or shift work disorder; Parkinson's disease; Alzheimer's disease; attention deficit disorder; attention deficit hyperactivity disorder; depression; or fatigue associated with a neurological disease; as well as the promotion of wakefulness.
REFERENCES:
patent: 3894034 (1975-07-01), Gassman et al.
patent: 3993683 (1976-11-01), Nickl et al.
patent: 4062973 (1977-12-01), Nickl et al.
patent: 4066686 (1978-01-01), Lafon
patent: 4120692 (1978-10-01), Plant et al.
patent: 4177290 (1979-12-01), Lafon
patent: 4191776 (1980-03-01), Nickl et al.
patent: 4216160 (1980-08-01), Dorn et al.
patent: 4329363 (1982-05-01), Dorn et al.
patent: 4582837 (1986-04-01), Hauel et al.
patent: 4696931 (1987-09-01), Hauel et al.
patent: 4744812 (1988-05-01), Parg et al.
patent: 4846875 (1989-07-01), Chang
patent: 4846882 (1989-07-01), Chang
patent: 4927855 (1990-05-01), Lafon
patent: 4935240 (1990-06-01), Nakai et al.
patent: 4959385 (1990-09-01), Cook et al.
patent: 4980372 (1990-12-01), Nakai et al.
patent: 5105017 (1992-04-01), Dillard
patent: 5180745 (1993-01-01), Lafon
patent: 5258433 (1993-11-01), Meier et al.
patent: 5391576 (1995-02-01), Lafon
patent: 5393768 (1995-02-01), Dillard
patent: 5401776 (1995-03-01), Laurent
patent: 5585359 (1996-12-01), Breslin et al.
patent: 5612379 (1997-03-01), Laurent
patent: 5719168 (1998-02-01), Laurent
patent: 5763539 (1998-06-01), Stern et al.
patent: 6346548 (2002-02-01), Miller et al.
patent: 6455588 (2002-09-01), Scammell et al.
patent: 6472414 (2002-10-01), Biller et al.
patent: 6488164 (2002-12-01), Miller et al.
patent: 6492362 (2002-12-01), Graupe et al.
patent: 6492396 (2002-12-01), Bacon et al.
patent: 6566404 (2003-05-01), Esteve et al.
patent: 6670358 (2003-12-01), Bacon et al.
patent: 6919367 (2005-07-01), Bacon et al.
patent: 6924314 (2005-08-01), Sharma et al.
patent: 7119214 (2006-10-01), Lesur et al.
patent: 7132443 (2006-11-01), Haffner et al.
patent: 7157463 (2007-01-01), Backer et al.
patent: 7268132 (2007-09-01), Bacon et al.
patent: 7297817 (2007-11-01), Lesur et al.
patent: 7314875 (2008-01-01), Bacon et al.
patent: 7423176 (2008-09-01), Bacon et al.
patent: 7449481 (2008-11-01), Bacon et al.
patent: 7476690 (2009-01-01), Lesur et al.
patent: 7759356 (2010-07-01), Heintzelman et al.
patent: 2003/0100548 (2003-05-01), Barlaam et al.
patent: 2003/0113751 (2003-06-01), Sem et al.
patent: 2008/0027228 (2008-01-01), Bacon et al.
patent: 2008/0070956 (2008-03-01), Bacon et al.
patent: 2009/0018143 (2009-01-01), Lesur et al.
patent: 2009/0042907 (2009-02-01), Bacon et al.
patent: 2009/0105241 (2009-04-01), Lesur et al.
patent: 25 45 947 (1977-04-01), None
patent: 0 001 989 (1978-10-01), None
patent: 1 140 748 (1969-01-01), None
patent: 1 178 279 (1970-01-01), None
patent: 1 570 982 (1976-03-01), None
patent: 1 469 083 (1977-03-01), None
patent: 1 600 840 (1978-05-01), None
patent: 45-28989 (1970-09-01), None
patent: 04-059754 (1992-02-01), None
patent: WO 87/04049 (1987-07-01), None
patent: WO 87/07602 (1987-12-01), None
patent: WO 91/17162 (1991-11-01), None
patent: WO 95/01171 (1995-01-01), None
patent: WO 96/09836 (1996-04-01), None
patent: WO 97/15555 (1997-05-01), None
patent: WO 98/08941 (1998-03-01), None
patent: WO 98/23588 (1998-06-01), None
patent: WO 99/25329 (1999-05-01), None
patent: WO 01/19796 (2001-03-01), None
patent: WO 01/87830 (2001-11-01), None
patent: WO 02/10125 (2002-02-01), None
patent: WO 02/069901 (2002-09-01), None
patent: WO 02/070469 (2002-09-01), None
patent: WO 03/037853 (2002-10-01), None
patent: WO 03/002531 (2003-01-01), None
patent: WO 03/023392 (2003-03-01), None
patent: WO 03/072561 (2003-09-01), None
Augeri, et al., Journal of Medicinal Chemistry, vol. 41, No. 22, 1998, pp. 4288-4300.
Boeckmann, et al., Chemische Berichte, vol. 114, No. 3, 1981, pp. 1048-1064.
Bradbury, et al., Journal of Medicinal Chemistry, vol. 35, No. 22, 1992 pp. 4027-4038.
Breslin, et al., Bioorganic & Medicinal Chemistry Letters, 8, 1998, pp. 3311-3316.
Brown, et al., Journal of Medicinal Chemistry, vol. 35, No. 20, 1992, pp. 3613-3624.
Costero, et al., Journal of Chemical Research, No. 4, 1994, pp. 761-769.
El Sakka et al., Arch. Pharm. , 327, 1994, pp. 133-135.
El-Zohry, Phosphorus, Sulfur, and Silicon, vol. 66, No. 14, 1992, pp. 311-319.
Faucher et al., J. Med. Chem, 47, 2004, pp. 18-21.
Graybill, et al., Tetrahedron Letters, vol. 43, No. 30, 2002, pp. 5305-5309.
Han et al., J. Org. Chem., 62, 1997, pp. 3841-3848.
Hermant et al., Psychipharmacaology, 103, 1991, pp. 28-32.
Iqbal et al., Drug Development Research, vol. 51, 2000, pp. 177-186.
Le Diguarher, et al., Journal of Medicinal Chemistry, vol. 46, No. 18, 2003, pp. 3840-3852.
McConachie, et al., Tetrahedron Letters, vol. 41, No. 30, 2002, pp. 5637-5641.
Nishikawa, et al., Takeda Kenkyusho Ho, Journal of the Takeda Research Laboratories, vol. 31, No. 3, 1972, pp. 331-348.
Nugent, et al., Journal of Medicinal Chemistry, vol. 41, No. 20, 1998, pp. 3793-3803.
Panckeri et al., Sleep, 19(8), 1996, pp. 626-631.
Picard, et al., Heterocycles, vol. 38, No. 8, 1994 pp. 1775-1789.
Segarra, et al., Bioorganic & Medicinal Chemistry Letters, vol. 8, No. 5, 1998, pp. 505-510.
Shelton et al., Sleep, 18(10), 1995, pp. 817-826.
Shiotsuki et al., Pesticide Biochemistry and Physiology, 37, 1990, pp. 121-129.
Sucholeiki, Tetrahedron Letters, vol. 35, No. 40, 1994, pp. 7307-7310.
Takeuchi, et al., Journal of Chemical Research, Miniprint, No. 12, 1991, pp. 3156-3188.
Touret et al., Neuroscience Letters, 189, 1995, pp. 43-46.
Suzuki et al., Toyobo Fiber Laboratory, May 4, 1967, pp. 583-587.
Dostert P. and Jalfre M.,Eur. J. Med. Chem., 1974, 9(3), 259-262.
Saenz R.V. and Sowell J.W.,J. Pharm. Sci., 1972, 61(6), 978-980.
Portevin, B. et al.,J. Med. Chem., 1996, 39, 2379-2391.
Bacon Edward R.
Chatterjee Sankar
Dunn Derek
Gourdel Marie-Edith
Hostetler Greg
Cephalon France
Cephalon Inc.
Shiao Rei-tsang
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