Thio-.beta.-lactam cephalosporins

Details Thio-.beta.-lactam cephalosporins Thio-.beta.-lactam cephalosporins

1976-10-22

1977-08-02

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424246, C07D50118

Patent

active

040395375

ABSTRACT:
Thio-.beta.-lactam cephalosporins of the general formula ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, trihaloethyl, alkali metal or alkaline earth metal; R.sub.1 is hydrogen, lower alkyl, cycloalkyl, phenyl, phenoxy, phenyl-lower alkyl or certain heterocyclic groups; R.sub.2 is hydrogen, amino, carboxy, hydroxy or ureido; and X is hydrogen, hydroxy, lower alkylthio, lower alkylthiadiazolyl, lower alkyltetrazolyl or lower alkanoyloxy, are useful as antimicrobial agents.

REFERENCES:
patent: 3971780 (1976-07-01), Cimarusti et al.

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