Thin layer chromatography direct sample application manifold

Details Thin layer chromatography direct sample application manifold Thin layer chromatography direct sample application manifold

1991-07-15

1994-06-14

Warden, Robert J.

Chemical apparatus and process disinfecting, deodorizing, preser

Control element responsive to a sensed operating condition

422 70, 422 89, 422104, 2101983, B01L 1100

Patent

active

053208110

ABSTRACT:
An apparatus and method for directly applying a liquid sample matrix containing analytes and possible endogenous compounds to selected areas of a thin layer chromatographic sheet. The apparatus comprises a manifold made from an upper and lower filter block which are fastened together and supported on a support member. The thin layer chromatographic sheet is held between the upper and lower filter block. Samples are applied to the thin layer chromatographic sheet through aligned through-bores in the upper and lower filter block by connecting a syringe to the through-bores of the upper filter block. The method involves initially wetting areas of the thin layer chromatographic sheet where the sample is subsequently applied. Analytes retained on the thin layer chromatographic sheet are subsequently analyzed and may be further extracted from the thin layer chromatographic sheet for analysis.

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