Thin film membrane enzyme reactor and method of using same

Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...

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210632, 435176, 435177, 435182, 435817, C12N 1102, C12N 1108, C12N 1114

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active

049562894

ABSTRACT:
An enzyme reactor system is provided based on the entrapment of an enzyme in a hydrogel layer coated on a support, and confined by an ultraporous thin film membrane diffusion barrier. The diffusion barrier confines the enzyme, but lets substrate and reaction products diffuse feeely into and out of the hydrogel layer. In an alternate embodiment, the support is formed of an ultraporous thin film membrane diffusion barrier on a microporous or macroporous support, through which the reaction products can diffuse freely, but through which neither enzyme nor substrate can pass. In this embodiment, the product is recovered in high purity, free of substrate and enzyme.

REFERENCES:
patent: 3979274 (1976-09-01), Newman
patent: 4307195 (1981-12-01), Karasawa et al.
patent: 4404066 (1983-09-01), Johnson
patent: 4545382 (1985-10-01), Higgens et al.
patent: 4795704 (1989-01-01), Matson

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