Thienyoxy and furyl containing analogs of prostacyclin and their

Details Thienyoxy and furyl containing analogs of prostacyclin and their Thienyoxy and furyl containing analogs of prostacyclin and their

1980-01-23

1982-01-26

Ford, John M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Allergen or component thereof

424285, 542426, 542430, C07D307935, C07D30332, A61K 31557

Patent

active

043128823

ABSTRACT:
What is disclosed are prostacyclin analogs of the general formula I ##STR1## which have a more specific action and/or a longer action than the naturally occurring prostacyclin PGI.sub.2, as well as intermediate products for their preparation and a process for their preparation. The compounds of formula I are distinguished by inhibitory action on thrombocyte aggregation and by relaxation of the vascular walls, in particular of the coronary arteries. They can thus be used as medicaments.

REFERENCES:
patent: 4158667 (1979-06-01), Axen
patent: 4178367 (1979-12-01), Hayashi et al.
patent: 4219479 (1980-08-01), Vorbruggen et al.

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