Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-10-31
2006-10-31
Shameem, Golam M. M. (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C548S255000, C548S266200, C548S315700
Reexamination Certificate
active
07129361
ABSTRACT:
The thienylazolylalkoxyethanamines (I) where R1 is a hydrogen atom, a halogen atom or a lower alkyl radical; R2, R3 and R4 represent, independently, a hydrogen atom or a lower alkyl radical; and Az represents a five-member nitrogenated hetercyclic aromatic group, N-methyl-substituted, that contains from one to three nitrogen atoms. They have analgesic activity in mammals, including humans. The compounds (I) can be obtained, for example, by reaction of a derivative of hydroxy-thienylazol (IV) with a derivative of a suitable N-(ethyl)amine. The compounds (IV) are useful intermediates in the synthesis of the compounds (I). The compounds (I) have an application in human and/or veterinary medicine.
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Mattioli, F. et al. “W-Dialkylaminoalkyl Ethers . . . ” J. Of Heterocyclic Chemistry, Vo. 34, p. 963-968 (1997).
Andaluz-Mataro Blas
Frigola-Constansa Jordi
Merce-Vidal Ramon
Laboratorios del Dr. Esteve S.A.
Ladas & Parry LLP
Sackey Ebenezer
Shameem Golam M. M.
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