Thienothiazines

Details Thienothiazines Thienothiazines

1975-08-21

1978-02-28

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

2603322C, 424246, C07D51304

Patent

active

040767094

ABSTRACT:
The present invention relates to compounds of the formula ##STR1## wherein A together with the two carbon atoms to which it is attached forms the group ##STR2## AND THE BROKEN LINE REPRESENTS THE DOUBLE BOND IN GROUP (A); R.sub.1 represents a lower alkyl group; R.sub.2 represents the residue of an aromatic heterocyclic ring containing from 1 to 4 hetero atoms, which may be substituted by one or two lower alkyl groups, or a phenyl group which may be substituted by halogen, hydroxy, lower alkyl, trifluoromethyl or lower alkoxy and R.sub.3 and R.sub.4 each represent a hydrogen atom or a lower alkyl group.
Also provided are methods for their preparation. The thienothiazine derivatives provided by this invention have anti-flammatory, analgesic and antirheumatic activity.

REFERENCES:
patent: 3923801 (1975-12-01), Rasmussen
patent: 3925371 (1975-12-01), Rasmussen
patent: 3927002 (1975-12-01), Lombardino

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