Thienopyrroles as antiviral agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C540S471000

Reexamination Certificate

active

07973026

ABSTRACT:
The present invention relates to tetracyclic thienopyrrole compounds of formula (I), wherein Ar, A, D1, D2, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus.

REFERENCES:
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patent: WO 02/059321 (2002-08-01), None
patent: WO 2005/023819 (2005-03-01), None
Kim, Microbes and Infection, 2002, 4, 1219-25.
“Cirrhosis-Prevention”, http://www.mayoclinic.com/health/cirrhosis/DS00373/DSECTION=prevention, accessed Jul. 5, 2010.
Licia Tomei et al., 81 Journal of General Virology 759-67 (2000).
V. Lohmann et al., 285 Science 110-13 (1999).
Volker Lohmann et al., 274(16) The Journal of Biological Chemistry 10807-15 (1999).
W. Clark Still et al., 43(14) Journal of Organic Chemistry 2923-25 (1978).

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