Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-11-24
1994-01-18
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544278, 549 69, 549 70, C07D49504, C07D33338, A61K 31505
Patent
active
052800261
ABSTRACT:
Thienopyrimidine compounds are disclosed as inhibitors of the H.sup.+ K.sup.+ ATPase enzyme useful in the treatment of gastric acid secretion. A compound of the invention is 2-(2-methylphenylamino)-4-(N-methylphenylamino)thieno[3,2-d]pyrimidine.
REFERENCES:
patent: 3931204 (1976-01-01), Croisier
patent: 4146716 (1979-03-01), Cox et al.
patent: 4196207 (1980-04-01), Webber
patent: 5124331 (1992-06-01), Arita
Robba, Bull. Chem. Soc. France, Pt 2, 592-597 (1975).
Brown Thomas H.
Ife Robert J.
Leach Colin A.
Berch Mark L.
Hall Linda E.
Lentz Edward T.
SmithKline Beecham Intercredit B.V.
Suter Stuart R.
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