Thienopyridine derivatives, their production and use

Details Thienopyridine derivatives, their production and use Thienopyridine derivatives, their production and use

2006-06-27

2006-06-27

Davis, Zinna Northington (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S080000

Reexamination Certificate

active

07067527

ABSTRACT:
The present invention provides thienopyridine derivatives, which are useful as anti-inflammatory drugs, particularly as remedies for arthritis; processes for producing them, and pharmaceutical compositions containing them. The thienopyridine derivatives are represented by the formula (I):wherein G is a halogen atom, hydroxyl group, an optionally substituted amino group, etc.; alk is an optionally substituted lower alkylene group; X is O, S, —(CH2)q—, etc.; R is an optionally substituted amino group, etc.; ring B is an optionally substituted Y-containing 5- to 8-membered ring whose ring constituent atoms contain no nitrogen atom; Y is O, S, a group of(wherein Ra, Rb and Rc are the same or different and, each is H, a halogen atom, an optionally substituted hydrocarbon group, etc.), etc.; and ring A may be substituted.

REFERENCES:
patent: 5747486 (1998-05-01), Sohda et al.
patent: 6046189 (2000-04-01), Sohda et al.
patent: 6214838 (2001-04-01), Sohda et al.
patent: 6653476 (2003-11-01), Yasuma et al.

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