Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1978-01-18
1978-11-28
Raymond, Richard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
548309, A01N 912, C07D49510
Patent
active
041276655
ABSTRACT:
Novel spiro-thienohydantoin derivatives useful as aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications are disclosed. Preferred compounds include 6,7-dihydro-spiro-[benzo(b)thiophene-4(5H),4'-imidazolidine]-2',5'-dione, 2-chloro-spiro-[cyclopenta(b) thiophene-4,4'-imidazolidine]-2',5'-dione, spiro-[cyclopenta(c)thiophene-4,4'-imidazolidine]-2',5'-dione, 1-chloro-spiro[cyclopenta(c)thiophene-4,4'-imidazolidine]-2',5'-dione and 1,3-dichloro-spiro[cyclopenta(c)thiophene-4,4'-imidazolidine]-2',5'-dione.
Sarges Reinhard
Schnur Rodney C.
Knuth Charles J.
Murphy Francis X.
Pfizer Inc.
Raymond Richard
Richardson Peter C.
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