Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-04-23
2010-06-29
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S234200, C514S248000, C544S278000, C544S117000, C544S234000, C544S235000
Reexamination Certificate
active
07745449
ABSTRACT:
The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation and related conditions. The compounds have a general Formula Iwherein A1, A2, B, R2and R3are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, uses of such compounds and compositions for treatment of kinase mediated diseases including rheumatoid arthritis, psoriasis and other inflammation disorders, as well as intermediates and processes useful for the preparation of compounds of Formula I.
REFERENCES:
patent: 6635644 (2003-10-01), Salituro et al.
patent: 6794380 (2004-09-01), Brown
patent: 7091347 (2006-08-01), Chen et al.
patent: 7427616 (2008-09-01), Luke et al.
patent: 50140487 (1975-11-01), None
patent: 50140487 (1975-11-01), None
patent: 9716442 (1997-05-01), None
patent: 2004010995 (2004-02-01), None
patent: 2004013141 (2004-02-01), None
patent: WO 2004013141 (2004-02-01), None
patent: 2004041285 (2004-05-01), None
patent: 2005009937 (2005-02-01), None
patent: WO 2006/019768 (2006-02-01), None
Griesser, Chapter 8, The Importance of Solvates (pp. 211-230), in the text, Polymorphism: In the Pharmaceutical Industry, Hilfiker, 2006.
http://en.wikipedia.org/wiki/Derivative—(chemistry), Jun. 23, 2008, downloaded,Nov. 12, 2008.
Schreiber, et al., Clin. Gastroenterol. Hepatol., Mar. 2006, 4(3): 325-334 (PubMed abstract).
Newton, et al., Drug Discovery Today: Disease Mechanisms, 2006, 53-61.
Feldmann, Nature Immunology, vol. 2, No. 9, Sep. 2001, 771-773.
Hashimoto, et al., J. Pharmacol. & Exper. Therap., vol. 293, No. 2, 370-375, 2000.
Dodeller, Arth. Res. & Therapy 2006, 8:205.
Chandrasekhar et al., Clinical Immunol Immunopathol., 55:382 (1990).
Feldmann et al., Immunological Reviews, 195-223 (1995).
Shohami et al., J. Cereb. Blood Flow Metab. 14:615 (1994).
Falsey James R.
Hong Fang-Tsao
Rzasa Robert M.
Tadesse Seifu
Tasker Andrew
Amgen Inc.
Jaisle Cecilia M
Reddy G. Prabakhar
Wilson James O
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