Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1977-09-15
1978-10-31
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
26037631, C07D48704, A61K 3140
Patent
active
041235479
ABSTRACT:
Thienamycin sulfoxide (I, n=1), Thienamycin sulfone (I, n=2), and their pharmaceutically acceptable salts are disclosed to be useful as antibiotics: ##STR1## Also disclosed are processes for the preparation of such compounds, pharmaceutical compositions comprising such compounds, and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.
REFERENCES:
patent: 3950357 (1976-04-01), Kahan et al.
patent: 4000129 (1976-10-01), Verwey
patent: 4022773 (1977-05-01), Ishimaru
Fieser et al.; Advanced Organic Chemistry, p. 313 (1961).
Christensen Burton G.
Walton Edward
Arno James A.
Daus Donald G.
Levitt Julian S.
Mahon Frank M.
Merck & Co. , Inc.
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