Thiazolylacelamide cephalosporins

Details Thiazolylacelamide cephalosporins Thiazolylacelamide cephalosporins

1978-11-24

1982-04-27

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

424246, 544 21, 544 26, C07D50136

Patent

active

043272100

ABSTRACT:
Acyl derivatives of the formula ##STR1## wherein R signifies hydrogen or a protective group which can be split off, R.sup.1 signifies lower alkyl and X signifies the group ##STR2## wherein one of the residues R.sup.2 and R.sup.3 represents hydrogen and the other represents alkyl and R.sup.4 represents lower alkyl
the easily hydrolyzable esters and ethers thereof, the salts and hydrates of the above compounds, esters, ethers and salts.

REFERENCES:
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patent: 4091211 (1978-05-01), Montavon et al.
patent: 4098888 (1978-07-01), Ohiai et al.
patent: 4178442 (1979-12-01), Montavon et al.
patent: 4200745 (1980-04-01), Katner
Reiner, Jour. of Antibiotics, vol. 33, No. 7, pp. 783-786 (1980).
Schaad et al., Journ. of Infectious Diseases, vol. 143, No. 2 (1981), pp. 156-163.
Seddon, Antimicrobial Agents and Chemotherapy, vol 18, No. 2 (Aug. 1980), pp. 240-242.

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