Thiazolopyridinone derivates as MCH receptor antagonists

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

Reexamination Certificate

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C544S128000, C544S362000, C546S114000

Reexamination Certificate

active

07902356

ABSTRACT:
The present invention relates to a melanin concentrating hormone antagonist compound of formula (I); wherein w, R1, q, p, R2, t, Ar1, L1, R3and R4are as defined, or a pharmaceutically acceptable salt, solvate, or enantiomer thereof useful in the treatment, prevention or amelioration of symptoms associated with obesity and related diseases.

REFERENCES:
patent: 1 283 199 (2003-02-01), None
patent: 03/033476 (2003-04-01), None
patent: WO 03/033476 (2003-04-01), None
patent: WO 2004/052848 (2004-06-01), None
patent: 2005/047293 (2005-05-01), None
patent: 2007/093364 (2007-08-01), None
Carpenter, et al., “Melanin-concentrating hormone receptor antagonists as potential antiob,” Expert Opinion on Therapeutic Patents, Ashley Publications, GB, vol. 12, No. 11, pp. 1639-1646 (2002).
Dyck, et al., “A Thienopyridazinone-Based Melanin-Concentrating Hormone Receptor 1 Antagonist with Potent in Vivo Anorectic Properties,” Journal of Medicinal Chemistry, American Chemical Society, vol. 49, No. 13, pp. 3753-3756 (2006).

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